Drugs, leads, and drug-likeness: an analysis of some recently launched drugs.
Bioorg Med Chem Lett
; 12(12): 1647-50, 2002 Jun 17.
Article
em En
| MEDLINE
| ID: mdl-12039582
ABSTRACT
An analysis of the origins of recently launched drugs reveals that most were derived by modification of known drug structures or from lead structures obtained from the scientific literature. High-throughput screening did not have a significant impact on the derivation of these drugs. The drug structures are very closely related to their leads.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desenho de Fármacos
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article