Expression of the myogenic regulatory factor Mrf4 precedes or is contemporaneous with that of Myf5 in the somitic bud.
Mech Dev
; 117(1-2): 331-5, 2002 Sep.
Article
em En
| MEDLINE
| ID: mdl-12204280
ABSTRACT
The development of skeletal muscle in vertebrate embryos is controlled by a transcriptional cascade involving the four myogenic regulatory factors. In the somites of the mouse embryo the order of expression is thought to be Myf5, Myogenin, Mrf4 and MyoD. We have re-examined the expression pattern of Mrf4 and show that in the hypaxial domain of thoracic somites (the somitic bud) Mrf4 expression precedes or is contemporaneous with that of Myf5, suggesting that this transcription factor plays a hitherto unsuspected role in myogenesis.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transativadores
/
Fatores de Regulação Miogênica
/
Somitos
/
Desenvolvimento Muscular
/
Proteínas de Ligação a DNA
/
Proteínas Musculares
Limite:
Animals
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article