Repeated detection of gas in the portal vein after liver transplantation: A sign of EBV-associated post-transplant lymphoproliferation?
Pediatr Transplant
; 6(4): 332-6, 2002 Aug.
Article
em En
| MEDLINE
| ID: mdl-12234275
ABSTRACT
A 1-yr-old child presented with intractable right sided pleural effusion and progressive clinical deterioration 3 weeks after liver transplantation for Alagille Syndrome. He had been treated successfully for severe acute rejection before. Ultrasound and Doppler mode studies repeatedly demonstrated air in the portal vein. Intra-abdominal and intra-thoracic lymphoproliferation was detected, and EBV virus load and serology were suggestive of primary EBV infection. Liver biopsy revealed blast-like infiltrates of B-cells, considered diagnostic for post-transplant lymphoproliferative disease. The disease resolved upon reduction of immunosuppression. We suggest that the detection of portal vein gas in pediatric liver transplant recipients beyond the early post-operative period may be a sign of intra-abdominal post-transplant lymphoproliferative disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Veia Porta
/
Transplante de Fígado
/
Infecções por Vírus Epstein-Barr
/
Imunossupressores
/
Transtornos Linfoproliferativos
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Infant
/
Male
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article