A convenient method for the conversion of N-acyloxazolidinones to hydroxamic acids.
Org Lett
; 4(20): 3343-6, 2002 Oct 03.
Article
em En
| MEDLINE
| ID: mdl-12323014
ABSTRACT
Treatment of N-acyloxazolidinones with hydroxylamines using samarium triflate as a Lewis acid provides the corresponding hydroxamic acids in 50-98% yields at room temperature. The conversion proceeds with high degree of chemoselectivity and without racemization of chiral centers alpha- to the acyl group. [reaction see text]
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxazolidinonas
/
Ácidos Hidroxâmicos
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article