Risk factors for the development of primary cutaneous malignant melanoma.
Dermatol Clin
; 20(4): 597-600, 2002 Oct.
Article
em En
| MEDLINE
| ID: mdl-12380046
ABSTRACT
It is now possible to identify a small number of genes in which identifiable abnormalities are associated with an increased risk of melanoma, and a large number of phenotypic factors, which are associated with a lesser risk affecting a very much larger proportion of the melanoma population. As with colon cancer, it seems likely that there is a stepwise development of invasive malignant melanoma, and that interaction between genotype and environmental stimuli may be very different at each successive stage of melanoma progression. Unraveling these steps is the current challenge.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Neoplasias Cutâneas
/
Quinases Ciclina-Dependentes
/
Genes p16
/
Proteína Supressora de Tumor p14ARF
/
Melanoma
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article