Directed dihydroxylation of cyclic allylic alcohols and trichloroacetamides using OsO4/TMEDA.
J Org Chem
; 67(23): 7946-56, 2002 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-12423122
ABSTRACT
The oxidation of a range of cyclic allylic alcohols and amides with OsO4/TMEDA is presented. Under these conditions, hydrogen bonding control leads to the (contrasteric) formation of the syn isomer in almost every example that was examined. Evidence for the bidentate binding of TMEDA to OsO4 is presented and a plausible mechanism described.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article