Ketene dithioacetals in the aza-Diels-Alder reaction with N-arylimines: a versatile approach to tetrahydroquinolines, 2,3-dihydro-4-quinolones, and 4-quinolones.
Org Lett
; 4(25): 4411-4, 2002 Dec 12.
Article
em En
| MEDLINE
| ID: mdl-12465900
ABSTRACT
[reaction see text] The first successful use of ketene dithioacetals as dienophiles in the aza-Diels-Alder reaction with N-arylimines is described. Among the ketene dithioacetals tested, 1,4-benzodithiafulvenes are most effective in assembling the tetrahydroquinoline core. Subsequent chemical manipulations provide a concise and divergent approach to the synthesis of 2,3-tetrahydroquinolines, 2,3-dihydro-4-quinolones, and 4-quinolones.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article