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Death in bathtub revisited with molecular genetics: a victim with suicidal traits and a LQTS gene mutation.
Lunetta, P; Levo, A; Männikkö, A; Penttilä, A; Sajantila, A.
Afiliação
  • Lunetta P; Department of Forensic Medicine, University of Helsinki, PO Box 40, Helsinki 00014, Finland.
Forensic Sci Int ; 130(2-3): 122-4, 2002 Dec 04.
Article em En | MEDLINE | ID: mdl-12477631
A 44-year-old woman with a medical history of mental disorders and previous suicidal behaviour was found in a bathtub and pronounced death few minutes later despite of resuscitation attempts. After police investigation and on the basis of autopsy findings, the death was classified as suicide drowning. Retrospective examination of clinical data revealed, a prolonged rate-corrected QT-interval (QTc: 468 ms) 3 months before death. Post-mortem (PM) DNA analysis disclosed KCNH2(FIN) mutation for the long-QT syndrome (LQTS). The value of PM molecular screening for LQTS is emphasised, especially for victims of putative drowning.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome do QT Longo / Afogamento / Mutação Tipo de estudo: Observational_studies Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2002 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome do QT Longo / Afogamento / Mutação Tipo de estudo: Observational_studies Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2002 Tipo de documento: Article