3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.
J Med Chem
; 46(3): 353-5, 2003 Jan 30.
Article
em En
| MEDLINE
| ID: mdl-12540233
ABSTRACT
Selective adenosine A(3) agonists have potential utility for the prevention of perioperative myocardial ischemic injury. Herein, we report on the discovery and synthesis of compound 7. This amino nucleoside agonist possesses unprecedented levels of selectivity for the human adenosine A(3) receptor.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adenosina
/
Agonistas do Receptor Purinérgico P1
/
Isoxazóis
Limite:
Humans
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article