[Risk factors associated with ceftazidime-resistant Klebsiella pneumoniae infection]. / Factores de riesgo asociados a infecciones por Klebsiella pneumoniae resistentes a ceftacidima.
Enferm Infecc Microbiol Clin
; 21(2): 72-6, 2003 Feb.
Article
em Es
| MEDLINE
| ID: mdl-12586029
ABSTRACT
INTRODUCTION:
Risk factors associated with ceftazidime-resistant Klebsiella pneumoniae (CAZ-R Kp) infection may vary among hospitals and in the same hospital at different time points. Knowledge of these factors is required to establish suitable infection control programs.METHODS:
A case-control study was conducted to assess risk factors for CAZ-R Kp infection. Thirty-two cases were compared with 28 controls admitted to a 200-bed general hospital during 1999 and 2000.RESULTS:
In the univariate analysis Kp CAZ-R isolates were significantly associated with nosocomial acquisition (OR 5 17.40), prior antibiotic use (OR 5 14.94), particularly ciprofloxacin use (OR 5 5), and hospitalization stay of more than 6 days (OR 5 6.72). Significantly associated variables in the logistic regression analysis included nosocomial acquisition (OR 5 9.29), prior antibiotic use (OR 5 6.21), and particularly, ciprofloxacin use (OR 5 10.84).CONCLUSIONS:
Efforts toward more rational overall antibiotic use and particularly ciprofloxacin use, combined with infection control measures are necessary to decrease the prevalence of CAZ-R Kp in our hospital.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Klebsiella
/
Ceftazidima
/
Infecção Hospitalar
/
Resistência às Cefalosporinas
/
Klebsiella pneumoniae
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do sul
/
Argentina
Idioma:
Es
Ano de publicação:
2003
Tipo de documento:
Article