HLA typing does not predict REM sleep behaviour disorder and hallucinations in Parkinson's disease.

Onofrj, Marco; Luciano, Anna Lisa; Iacono, Diego; Thomas, Astrid; Stocchi, Fabrizio; Papola, Franco; Adorno, Domenico; Di Mascio, Rocco

Onofrj, Marco; Luciano, Anna Lisa; Iacono, Diego; Thomas, Astrid; Stocchi, Fabrizio; Papola, Franco; Adorno, Domenico; Di Mascio, Rocco.

Afiliação

Onofrj M; Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
Luciano AL; Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
Iacono D; Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
Thomas A; Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
Stocchi F; Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
Papola F; Regional Center for Immunohaematology and Tissue Typing, National Council of Research, L'Aquila, Italy.
Adorno D; Regional Center for Immunohaematology and Tissue Typing, National Council of Research, L'Aquila, Italy.
Di Mascio R; Institute of Medical Statistics. Università G. D'Annunzio, Chieti-Pescara, Italy.

Mov Disord ; 18(3): 337-340, 2003 Mar.

Article em En | MEDLINE | ID: mdl-12621640

ABSTRACT

ABSTRACT

HLA-DR2 haplotype and DQ1 DNA alleles, characterizing 90 to 100% of all narcoleptic patients, were found to be equally distributed in 20 Parkinson's disease (PD) patients with early hallucinations, rapid eye movement (REM) sleep-related behaviour disturbances (RBD), and sleep onset in REM (SOREM), and in 20 PD patients without hallucinations, despite 10 to 15 years of treatment, and no RBD or SOREM.

Assuntos

Alucinações/genética; Chaperonas Moleculares; Doença de Parkinson/genética; Transtorno do Comportamento do Sono REM/genética; Idoso; Proteínas de Transporte/genética; Feminino; Antígeno HLA-DR2/genética; Alucinações/diagnóstico; Haplótipos; Teste de Histocompatibilidade; Humanos; Masculino; Transtorno do Comportamento do Sono REM/diagnóstico; Estudos de Amostragem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Chaperonas Moleculares / Transtorno do Comportamento do Sono REM / Alucinações Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2003 Tipo de documento: Article

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