Pyridazinones as selective cyclooxygenase-2 inhibitors.
Bioorg Med Chem Lett
; 13(4): 597-600, 2003 Feb 24.
Article
em En
| MEDLINE
| ID: mdl-12639538
ABSTRACT
Pyridazinone was found to be an excellent core template for selective COX-2 inhibitors. Two potent, selective and orally active COX-2 inhibitors, which were highly efficacious in rat paw edema and rat pyresis models, have been obtained.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piridazinas
/
Inibidores de Ciclo-Oxigenase
/
Isoenzimas
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article