Ultrastructural changes in animal fat associated lipoid pneumonia: report of two cases.
East Afr Med J
; 77(6): 340-2, 2000 Jun.
Article
em En
| MEDLINE
| ID: mdl-12858939
ABSTRACT
Traditional or cultural practices in different parts of the world where oils are used continue to produce lipoid pneumonia. We report the ultrastructural findings and observations in animal fat associated lipoid pneumonia from two children following a cultural practice of forced feeding with animal fat (ghee). Clinical findings showed an acute or chronic chest infection which failed to respond to anti-microbial therapy. X-ray and chest CT scan revealed collapse/consolidations of the right middle and left lower lobes. Histology and electron microscopy revealed thickening and destruction of the alveolar septa, filling of alveolar spaces with red blood cells and macrophage which contained both primary and secondary lysosomes. The alveolar walls contained mostly type II pneumocyte with most of them surrounded by thickened basement membranes with only a small portion of their surfaces exposed directly to the alveolar space where it showed numerous microvilli.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Lipoide
/
Gorduras na Dieta
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Child
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article