Effects of 16S rRNA gene mutations on tetracycline resistance in Helicobacter pylori.
Antimicrob Agents Chemother
; 47(9): 2984-6, 2003 Sep.
Article
em En
| MEDLINE
| ID: mdl-12937008
The triple-base-pair 16S rDNA mutation AGA(926-928)-->TTC mediates high-level tetracycline resistance in Helicobacter pylori. In contrast, single- and double-base-pair mutations mediated only low-level tetracycline resistance and decreased growth rates in the presence of tetracycline, explaining the preference for the TTC mutation in tetracycline-resistant H. pylori isolates.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA Ribossômico 16S
/
Resistência a Tetraciclina
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Helicobacter pylori
/
Mutação
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article