[Clinical observation on efficacy of ivermectin in the treatment of intestinal nematode infections].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
; 10(4): 279-82, 1992.
Article
em Zh
| MEDLINE
| ID: mdl-1303336
ABSTRACT
A total of 166 cases were divided into 3 groups group A comprised 55, group B 54 and group C 57 cases. Group A received ivermectin 0.1 mg/kg orally at a single dose, the cure rates were 100%, 3.8% and 50% for ascaris, hookworm and trichuris, infections respectively group B received ivermectin 0.2 mg/kg orally at a single dose, the corresponding cure rates were 95.5%, 11.8% and 76.5% respectively; group C received pyrantel pamoate 10 mg/kg orally at a single dose, the corresponding cure rates were 95.5%, 29.6% and 31.6% respectively. Although the cure rates were very low for hookworm infection in both group A and B, however, a number of adult worms of Ancylostoma duodenale and Necator americanus were expelled aster medication; It indicates that ivermectin has some effects on these two species of human hookworm. Side effects were mild and transient in all groups.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ivermectina
/
Enteropatias Parasitárias
/
Infecções por Nematoides
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
/
Adult
/
Animals
/
Humans
Idioma:
Zh
Ano de publicação:
1992
Tipo de documento:
Article