[Leopard spot chorioretinopathy. Initial manifestation of recurrent acute lymphocytic leukemia]. / Leopardenfleck-Chorioretinopathie. Erstes Anzeichen eines Rezidivs einer akuten lymphozytischen Leukämie.
Ophthalmologe
; 89(5): 430-1, 1992 Oct.
Article
em De
| MEDLINE
| ID: mdl-1304225
ABSTRACT
An 11-year-old girl with a history of acute lymphocytic leukemia of the central nervous system had attained complete remission for almost 3 1/2 years after combination chemotherapy and radiotherapy when she developed iritis and chorioretinopathy of the right eye. Neither an anterior chamber tap nor a diagnostic vitrectomy revealed leukemic cells. Both nonspecific anti-inflammatory therapy and antiviral treatment were unsuccessful. Finally, lymphoblasts were detected in the cerebrospinal fluid and in the bone marrow after repeated lumbar puncture and bone marrow aspiration. Combination chemotherapy alone was resumed, resulting in the resolution of all acute ocular symptoms and bone marrow involvement. Only the leopard-spot-like pigmentary fundus changes persisted. The child has now remained in continuous complete remission for 1 1/2 years.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Retinianas
/
Síndrome de Necrose Retiniana Aguda
/
Neoplasias da Coroide
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Neoplasias Oculares
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
De
Ano de publicação:
1992
Tipo de documento:
Article