[Estimation of renal tubular function after uropoline administration in certain disease states]. / Ocena czynnosci cewek nerkowych po podaniu uropoliny w niektórych stanach chorobowych.
Przegl Lek
; 49(11): 362-4, 1992.
Article
em Pl
| MEDLINE
| ID: mdl-1306567
ABSTRACT
24 h urinary excretion of beta-microglobulin (beta 2M) and Tamm-Horsfall protein (THP) before and after administration 40 ml of 75% Uropoline were assessed, as a specific markers of proximal and distal tubular dysfunction respectively. 22 patients without renal diseases and hypertension (C), 22 hypertensive patients (HP), 14 patients with renal stone disease (RSD) and 16 patients with pyelonephritis (PN) were examined. Administration of Uropoline did not change beta 2M and THP urinary excretion in C, but increased beta 2M excretion in HP and decreased THP urinary excretion in patients with RSD. It is concluded, that Uropoline shows a noxious effect on the proximal tubule in HP and on the distal tubule in patients with RSD.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Diatrizoato de Meglumina
/
Meios de Contraste
/
Diatrizoato
/
Nefropatias
/
Testes de Função Renal
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
Pl
Ano de publicação:
1992
Tipo de documento:
Article