Testicular circulatory isolation: a phase I study.
Surg Oncol
; 1(6): 413-6, 1992 Dec.
Article
em En
| MEDLINE
| ID: mdl-1341279
ABSTRACT
Antineoplastic agents may damage germinal epithelium. Testicular circulatory isolation (TCI) is a regional drug exclusion technique designed to minimize this. We evaluated the technical and anaesthetic aspects of TCI in 10 patients who underwent bilateral orchiectomy immediately thereafter. A modified aortic clamp was placed trans-scrotally across the left testicular pedicle without pre-medication or anaesthesia and left in place for 1 h, occluding testicular blood flow. Minimal pain and anxiety were reported during the procedure. There were no complications related to TCI in any patient. This study supports the institution of trials of TCI in young men about to receive fertility-threatening chemotherapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testículo
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article