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[The synthesis of new pyrrolidone derivatives with psychotropic action]. / Sinteza unor noi derivati pirolidonici cu actiune psihotropa.
Stefanescu, E; Petrovanu, M; Ciocoiu, I; Caprosu, M; Bîcu, E.
Afiliação
  • Stefanescu E; Universitatea de Medicina si Farmacie Iasi.
Rev Med Chir Soc Med Nat Iasi ; 96(3-4): 241-2, 1992.
Article em Ro | MEDLINE | ID: mdl-1344862
ABSTRACT
The synthesis of ten new heterocyclic compounds obtained by the addition of pyrrolidone to heterocumulenes and its condensation or of its sodic derivative with acid chlorides is presented. The synthetized pyrolidonic derivatives were subjected to a preliminary study for determining their possible psychotropic action. The pharmacological screening evidenced a significant hypothermisante and neurodynamic-nootropic action of some synthetized compounds.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psicotrópicos / Pirrolidinonas Limite: Animals Idioma: Ro Ano de publicação: 1992 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psicotrópicos / Pirrolidinonas Limite: Animals Idioma: Ro Ano de publicação: 1992 Tipo de documento: Article