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Partial pancreaticoduodenectomy (Whipple procedure) for pancreatic malignancy: occlusion of a non-anastomosed pancreatic stump with fibrin sealant.
Marczell, A P; Stierer, M.
Afiliação
  • Marczell AP; Department of Surgery, Hanusch Medical Center, Vienna, Austria.
HPB Surg ; 5(4): 251-9; discussion 259-60, 1992 Jun.
Article em En | MEDLINE | ID: mdl-1356420
Following partial pancreaticoduodenectomy for periampullary and pancreatic cancer, the complication and mortality rates are particularly high. Various approaches have aimed at improving the postoperative result, with less than complete success. The discouraging results of others, and our own dissatisfaction, led us to evaluate an atraumatic, sutureless method for management of the residual gland. Following head resection, the remaining pancreas is occluded with a fibrin sealant (Tisseel c, Immuno AG, Vienna) via injection into the pancreatic duct, which is then ligated and left free in the peritoneal cavity. Among 44 patients treated with this method, there were no perioperative deaths. Three patients developed local complications (2 fistulae, 1 pancreatitis) due to technical errors that presumably resulted in incomplete occlusion. Evaluation of patients after two to three years indicates that the endocrine function of the pancreas has been largely conserved despite ductal occlusion.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adesivo Tecidual de Fibrina / Pancreaticoduodenectomia Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 1992 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adesivo Tecidual de Fibrina / Pancreaticoduodenectomia Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 1992 Tipo de documento: Article