Carcinogenic effects of skin transplantation and immunosuppression in mice.
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol
; 87(3): 275-80, 1976 Dec 09.
Article
em En
| MEDLINE
| ID: mdl-138273
ABSTRACT
C3H and BlD2 mice received skin transplants from an animal of the other strain. Three groups were immunosuppressed for varying periods of time, and with different doses of vinblastine, cyclophosphamide, or azathioprine. Following transplantation, control animals received daily injections of NaCl. All animals developed tumours of lymphoreticular origin, which would indicate that immunosuppression is only a secondary cause for tumor development, with antigenic stimulation being the primary factor.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Pele
/
Imunossupressores
/
Neoplasias Experimentais
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
1976
Tipo de documento:
Article