A Mediterranean arbovirus: the Toscana virus.
J Neurovirol
; 9(6): 577-83, 2003 Dec.
Article
em En
| MEDLINE
| ID: mdl-14602570
ABSTRACT
Toscana virus (Bunyaviridae family, Phlebovirus genus) is a sandfly fever virus responsible for human neurological infections. Sandfly viruses are transmitted by insect vectors (Phlebotomus species) and the infection is present in climatic areas that allow the life cycle of the vector. The arthropode-borne Toscana virus is the etiologic agent of meningitis, meningoencephalitis, and encephalitis. The frequency of this neuropathic infection increases in the summer months, peaking in August in the endemic Mediterranean areas (Italy, Portugal, Spain, and Cyprus). Infection diagnosis is carried out by molecular assays and immunoenzymatic tests, which are rapid and sensitive. Recent studies have investigated the antigenic properties of the viral proteins (nucleoprotein N and surface glycoproteins G1 and G2), to better understand their immunogentic role.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psychodidae
/
Infecções por Bunyaviridae
/
Febre por Flebótomos
/
Vírus da Febre do Flebótomo Napolitano
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article