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Small cell lung cancer: from molecular biology to novel therapeutics.
Pisick, Evan; Jagadeesh, Simha; Salgia, Ravi.
Afiliação
  • Pisick E; Tufts- New England Medical Center, Tufts University School of Medicine, Boston, MA, USA.
J Exp Ther Oncol ; 3(6): 305-18, 2003.
Article em En | MEDLINE | ID: mdl-14678519
Small cell lung cancer (SCLC) is an aggressive tumor which metastasizes early. Patients with this disease have a poor prognosis even with immediate treatment. Because of the aggressive nature of this disease, all aspects of this tumor are studied extensively. This review will provide an update of the biology of SCLC at both the molecular and cellular levels. Cellular pathways and their relationship to cellular function will also be discussed. Treatment of both primary limited- and extensive-stage diseases as well as recurrent disease will be discussed including chemotherapy, thoracic radiotherapy, and surgery. The role of novel therapeutics being investigated will also be addressed.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Pequenas / Neoplasias Pulmonares Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2003 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Pequenas / Neoplasias Pulmonares Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2003 Tipo de documento: Article