[Analysis of the relative factors of the onset of repeated ectopic pregnancy].

ABSTRACT

OBJECTIVE: To determine the relative factors of the onset of repeated ectopic pregnancy. METHODS: The clinical data of the first time ectopic pregnancy of 28 cases with repeated ectopic pregnancy were analysed, and compared with those of 56 cases of non-repeated ectopic pregnancy onsetting at the same period. The factors measured included age at onset of disease, age at first coitus, gravidity, parity, methods of contraception, duration of amenorrhea, duration of vaginal bleeding, serum beta-human chorionic gonadotropin level, volume of intraperitoneal bleeding, types of ectopic pregnancy, methods of therapy and inflammation evidence of fallopian tube. Logistic regression analysis was performed to determine the relative factors for onset of repeated pregnancy. RESULTS: The risk factors and its odds ratio (OR) from the multivariate analysis were as follow anastomosis of the tube (62.74, P = 0.043), positive evidence of inflammation of the tube (54.85, P = 0.000), no contraception (11.29, P = 0.002), contraception by condom occasionally (4.75, P = 0.046); the protective factors and its OR were as follow therapy being salpingectomy and sterilization of the opposite tube (0.06, P = 0.049), oral contraception (0.10, P = 0.050) and pharmacotherapy (0.33, P = 0.002). CONCLUSIONS: The risk factors of onset of repeated ectopic pregnancy include anastomosis of the tube, positive evidence of inflammation of the tube, no contraception and contraception by condom occasionally; the protective factors include therapy being salpingectomy and sterilization of the opposite tube, oral contraception and pharmacotherapy.