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[Tetany due to excessive use of alcohol: a possible magnesium deficiency]. / Tetanie bij overmatig alcoholgebruik: mogelijk een magnesiumtekort.
Smets, Y F; Bokani, N; de Meijer, P H; Meinders, A E.
Afiliação
  • Smets YF; Leids Universitair Medisch Centrum, afd. Algemene Interne Geneeskunde, Postbus 9600, 2300 RC Leiden. yfesmets@lumc.nl
Ned Tijdschr Geneeskd ; 148(14): 641-4, 2004 Apr 03.
Article em Nl | MEDLINE | ID: mdl-15106311
ABSTRACT
Two alcoholic patients, a woman aged 64 and a man aged 69 years, were admitted with tetany. Both had severe electrolyte disorders, with low plasma levels of calcium, magnesium and potassium. Following mineral supplementation both patients recovered. Hypomagnesaemia plays a central role in the pathophysiology of this syndrome. Chronic alcohol abuse results in hypomagnesaemia in 30% of patients by decreasing renal tubular reabsorption. Hypomagnesaemia leads to suppression of parathyroid-hormone secretion, parathyroid-hormone resistance and vitamin-D suppression, resulting in hypocalcaemia. Hypomagnesaemia also causes kaliuresis leading to hypokalaemia. Supplementation with magnesium is crucial in the treatment of this combined electrolyte disorder.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetania / Alcoolismo / Magnésio / Deficiência de Magnésio Tipo de estudo: Etiology_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: Nl Ano de publicação: 2004 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetania / Alcoolismo / Magnésio / Deficiência de Magnésio Tipo de estudo: Etiology_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: Nl Ano de publicação: 2004 Tipo de documento: Article