Uniform vascular contrast enhancement and reduced contrast medium volume achieved by using exponentially decelerated contrast material injection method.
Radiology
; 231(3): 732-6, 2004 Jun.
Article
em En
| MEDLINE
| ID: mdl-15163812
ABSTRACT
PURPOSE:
To investigate in computed tomographic (CT) angiography whether an exponentially decelerated contrast medium injection, as compared with a standard constant-rate injection, can facilitate uniform vascular contrast enhancement with a reduced contrast material volume. MATERIALS ANDMETHODS:
CT angiography of the abdominal aorta was performed in 46 subjects by using an exponentially decelerated injectionmethod:
134 mL of contrast medium was injected for 40 seconds, starting at 4.0 mL/sec and decreasing exponentially to 2.7 mL/sec by the end of the injection. Twenty-one of these subjects also underwent CT angiography with a constant-rate injection 160 mL of contrast medium was injected for 40 seconds at a constant rate of 4 mL/sec. Time-enhancement curves and the magnitude of peak vascular enhancement were measured. Enhancement uniformity was evaluated by using three indexes (a) duration of contrast enhancement achieved within 80% of the peak (80% DCE), (b) SD of the normalized contrast enhancement (SDNCE) measured from the beginning of spiral CT scanning to the time when the enhancement decreased to a level lower than the beginning level, and (c) slope of the enhancement curve calculated by using linear regression analysis.RESULTS:
Exponentially decelerated injection resulted in more uniform enhancement. Mean values generated by using exponentially decelerated versus constant-rate injection in 21 paired comparisons were, respectively, 30.8 seconds +/- 5.0 versus 22.6 seconds +/- 7.6 for 80% DCE, 0.052 +/- 0.017 versus 0.086 +/- 0.031 for SDNCE, and 0.47 HU/sec +/- 0.70 versus 2.27 HU/sec +/- 0.87 for slope (P <.001 for all indexes). Compared with the peak enhancement resulting from the constant-rate injection, that resulting from the exponentially decelerated injection was reduced by a mean of 17.2% +/- 10.0.CONCLUSION:
Uniform vascular contrast enhancement and reduced contrast medium volume, which are desirable in CT angiography, can be achieved with exponentially decelerated injection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácidos Tri-Iodobenzoicos
/
Angiografia
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Tomografia Computadorizada por Raios X
/
Meios de Contraste
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article