Review of cytokine profiles in patients with hepatitis.
World J Gastroenterol
; 10(12): 1709-15, 2004 Jun 15.
Article
em En
| MEDLINE
| ID: mdl-15188491
ABSTRACT
The development of T helper 1 versus T helper 2 cells is a major branch point in the immune response and is an important determinant of the body's response to an infectious pathogen, leading to protection of the host or dissemination of the disease. Recent studies have shown that there exist macrophage activation states in parallel to the T helper cell type 1/2 paradigm, and the T helper 1 development process is governed to a great degree by cytokine IL-12 provided mainly by antigen presenting cells such as macrophages and dendritic cells. A model in patients with hepatitis is proposed that links the pathogen, macrophage activation and T helper cell polarization.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Citocinas
/
Células Th2
/
Células Th1
/
Hepatite
Limite:
Humans
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article