Antifungal constituents of Melicope borbonica.
Phytother Res
; 18(7): 542-5, 2004 Jul.
Article
em En
| MEDLINE
| ID: mdl-15305313
ABSTRACT
Fractionation of extracts of the leaves of Melicope borbonica (syn. Euodia borbonica var. borbonica), a medicinal plant from the Réunion Island that is traditionally used for wound healing and other ailments, afforded an acetophenone (xanthoxylin) and two coumarins, scoparone and limettin, as the major constituents. All three compounds exhibited moderate antifungal activity against Candida albicans and Penicillium expansum, in accordance with the traditional use of the plant. Moreover, 2,4,6-trimethoxyacetophenone (methylxanthoxylin), three other coumarins [7-(3-methyl-2-butenyloxy)-6-methoxycoumarin, cedrelopsin and psoralen], two sesquiterpenes (alpha-curcumene and 3,6-epidioxy-1,10-bisaboladiene), eugenol, methyleugenol and a lignan (sesamin) were isolated. None of the isolated constituents exhibited antiin fl ammatory activity in vitro. No alkaloids were detected.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Penicillium
/
Candida albicans
/
Extratos Vegetais
/
Rutaceae
/
Fitoterapia
/
Antifúngicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article