Expression of cell cycle-dependent genes and proliferative state of lymphocytes in aging.
Arch Gerontol Geriatr
; 11(2): 133-9, 1990.
Article
em En
| MEDLINE
| ID: mdl-15374484
ABSTRACT
The authors analyzed the expression of some genes involved in the control of T lymphocyte proliferation in a group of healthy elderly subjects. They focused their attention on genes involved in the G(0)/G(1) transition (TK, PCNA, H3, IL2-R) and showed decreased expression in the TK, H3 and IL2-R genes. Using flow cytofluorimetry, delayed transition from the G(0)/G(1) to the S stage was observed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article