Immunologic and genetic characterization of S180, a cell line of murine origin capable of growing in different inbred strains of mice.
Vet Immunol Immunopathol
; 30(4): 385-98, 1992 Jan 31.
Article
em En
| MEDLINE
| ID: mdl-1546443
ABSTRACT
Some of the immunologic and genetic properties of the cell line S180 have been examined. These cells grew without restrictions in the peritoneal cavity of different inbred strains of mice and invariably killed the animals. With Northern blots it was demonstrated that S180 cells contained class I mRNAs but failed to transcribe B2m genes. However, under experimental conditions, a protective humoral immune response mediated by cytotoxic antibodies and complement against S180 cells was obtained through non-H-2 antigens in C57BL/6J mice.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células Tumorais Cultivadas
/
Microglobulina beta-2
/
Antígenos de Neoplasias
Limite:
Animals
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article