Bupropion SR for relapse prevention: a "slips-allowed" analysis.
Am J Health Behav
; 28(5): 456-63, 2004.
Article
em En
| MEDLINE
| ID: mdl-15482975
ABSTRACT
OBJECTIVE:
To assess the efficacy of bupropion SR on smoking abstinence using a "slips allowed" analysis.METHODS:
Retrospective analysis, which did not consider brief episodic "slips" as a return to regular smoking, of data from a multicenter, randomized, doubleblind, placebo-controlled relapse prevention study.RESULTS:
Using a slips-allowed analysis, median time to relapse on bupropion SR was 65 weeks versus 30 weeks on placebo. This is compared to 32 and 20 weeks, respectively, using a traditional analysis not allowing for slips.CONCLUSION:
Bupropion SR is efficacious for the prevention of smoking relapse. A slips-allowed analysis may provide a more clinically relevant assessment of efficacy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fumar
/
Abandono do Hábito de Fumar
/
Bupropiona
/
Antidepressivos de Segunda Geração
/
Prevenção do Hábito de Fumar
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article