Acyclic nucleosides bearing a furanyl scaffold.
Nucleosides Nucleotides Nucleic Acids
; 24(1): 37-43, 2005.
Article
em En
| MEDLINE
| ID: mdl-15715197
ABSTRACT
Synthesis of acyclic nucleosides bearing a furanyl scaffold is described. The approach involved the construction of the base moiety onto a dihydrofuranyl intermediate. While the A and C analogues did exhibit some substrate activity toward deoxycytidine kinase, the compounds were devoid of any significant anti-HIV activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
HIV
/
Furanos
/
Nucleosídeos
Limite:
Humans
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article