Formation of an oxo-radical of peroxovanadate during reduction of diperoxovanadate with vanadyl sulfate or ferrous sulfate.
Biochim Biophys Acta
; 1722(1): 30-5, 2005 Feb 11.
Article
em En
| MEDLINE
| ID: mdl-15716128
ABSTRACT
Formation of oxygen radicals during reduction of H(2)O(2) or diperoxovanadate with vanadyl sulfate or ferrous sulfate was indicated by the 1221 electron spin resonance (ESR) signals of the DMPO adduct typical of standard ()OH radical. Signals derived from diperoxovanadate remained unchanged in the presence of ethanol in contrast to those from H(2)O(2). This gave the clue that they represent a different radical, possibly (*)OV(O(2))(2+), formed on breaking a peroxo-bridge of diperoxovanadate complex. The above reaction mixtures evolved dioxygen or, when NADH was present, oxidized it rapidly which was accompanied by consumption of dioxygen. Operation of a cycle of peroxovanadates including this new radical is suggested to explain these redox activities both with vanadyl and ferrous sulfates. It can be triggered by ferrous ions released from cellular stores in the presence of catalytic amounts of peroxovanadates.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peróxidos
/
Vanadatos
/
Compostos Ferrosos
/
Espécies Reativas de Oxigênio
/
Compostos de Vanádio
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article