The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase.
Acta Crystallogr D Biol Crystallogr
; 61(Pt 3): 309-15, 2005 Mar.
Article
em En
| MEDLINE
| ID: mdl-15735341
ABSTRACT
The single-crystal X-ray structure of phosphoglycerate mutase from Mycobacterium tuberculosis has been determined at a resolution of 1.70 angstroms. The C-terminal tail of each of the subunits is flexible and disordered; however, for one of the four chains (chain A) all but five residues of the chain could be modeled. Noteworthy features of the structure include the active site and a proline-rich segment in each monomer forming a short left-handed polyprolyl helix. These segments lie on the enzyme surface and could conceivably participate in protein-protein interactions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfoglicerato Mutase
/
Mycobacterium tuberculosis
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article