Good manufacturing practice production of adenoviral vectors for clinical trials.
Hum Gene Ther
; 16(3): 281-91, 2005 Mar.
Article
em En
| MEDLINE
| ID: mdl-15812223
ABSTRACT
The increasing importance of recombinant adenoviral vectors for gene therapy, cancer therapy, and the development of prophylactic and therapeutic vaccines has led to worldwide efforts toward scalable process development suitable for commercial manufacturing of replication-deficient adenoviral vectors. This review focuses on the manufacturing of adenovirus for clinical trials in the context of good manufacturing practice conditions and regulations.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cultura de Vírus
/
Terapia Genética
/
Adenoviridae
/
Tecnologia Farmacêutica
/
Vetores Genéticos
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article