Wnt/beta-catenin--a canonical tale of cell-fate choice in the vertebrate skeleton.
Dev Cell
; 8(5): 626-7, 2005 May.
Article
em En
| MEDLINE
| ID: mdl-15866155
ABSTRACT
Three exciting papers in this issue of Developmental Cell provide new insights into the regulation of chondrocytic, osteoblastic, and osteoclastic differentiation during skeletal development and postnatal growth. The studies demonstrate that Wnt/beta-catenin signaling represents both a mechanism in mesenchymal precursor cells for selecting between chondrocytic and osteoblastic fates as well as a mechanism in osteoblasts for stimulating the production of an inhibitor of osteoclast formation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desenvolvimento Ósseo
/
Transativadores
/
Proteínas do Citoesqueleto
/
Peptídeos e Proteínas de Sinalização Intercelular
Limite:
Animals
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article