Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7.
Haematologica
; 90(5): 691-3, 2005 May.
Article
em En
| MEDLINE
| ID: mdl-15921387
ABSTRACT
We report 14 cases of secondary myelodysplastic syndromes (sMDS) following treatment with azathioprine for non-malignant disorders. Long-term treatment with azathioprine seems to be associated with an increased risk of MDS and subsequent leukemic transformation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Azatioprina
/
Translocação Genética
/
Síndromes Mielodisplásicas
/
Cromossomos Humanos Par 7
/
Imunossupressores
/
Monossomia
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article