Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis.
Phytochemistry
; 66(10): 1174-9, 2005 May.
Article
em En
| MEDLINE
| ID: mdl-15924922
ABSTRACT
Two new prenylated anthronoids, harunmadagascarins A and B, were isolated from the stem bark of Harungana madagascariensis along with six known compounds including two anthronoids harunganol B and harungin anthrone, one benzophenone methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate and three pentacyclic triterpenes friedelin, lupeol and betulinic acid. Harunmadagascarins A and B were characterized as 8,9-dihydroxy-4,4-bis-(3,3-dimethylallyl)-6-methyl-2,3-(2,2-dimethylpyrano)anthrone and 8,9-dihydroxy-4,4,5-tris-(3,3-dimethylallyl)-6-methyl-2,3-(2,2-dimethylpyrano)anthrone, respectively. The structures of these secondary metabolites were determined by spectroscopic means and comparison with the published data. Methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate was isolated for the first time from a plant. Harunmadagascarins A and B, harunganol B and harungin anthrone exhibited significant antioxidant activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Clusiaceae
/
Casca de Planta
/
Antracenos
/
Antioxidantes
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article