In vivo prompt gamma neutron activation analysis of cadmium in the kidney and liver.

An existing McMaster University in vivo prompt gamma neutron activation analysis system has been improved in order to reduce the cadmium detection limit in the kidney and liver. The detection limit for the kidney was found to be 1.7 mg, a greater than factor of 2 improvement over the previous results obtained at McMaster. The liver detection limit was determined to be 3.3 ppm. The corresponding skin dose for these measurements was only 0.5 mSv. The effect of kidney position on the detection limit also was examined. Figures of merit were calculated in order to compare the performance of the current system to others.