Regulation of histone gene expression.
Curr Opin Cell Biol
; 4(2): 166-73, 1992 Apr.
Article
em En
| MEDLINE
| ID: mdl-1599687
ABSTRACT
Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory elements. The three-dimensional organization of the promoter and, in particular, its spatial relationship with the nuclear matrix scaffold, may be important factors of transcription regulation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Histonas
Limite:
Humans
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article