Homocysteine-lowering therapy and carotid intima-media thickness in renal transplant recipients.
Transplant Proc
; 37(6): 2491-2, 2005.
Article
em En
| MEDLINE
| ID: mdl-16182720
ABSTRACT
The aim of this study was to document, in hyperhomocysteinemic renal transplant recipients, the effect of vitamin supplementation on carotid intima-media thickness (cIMT). Fifty-six hyperhomocysteinemic stable renal transplant recipients were randomly assigned to either vitamin supplementation (group A) or placebo treatment (group B). All patients underwent high-resolution B mode ultrasound to measure IMT of common carotid arteries before and after 6 months of vitamin supplementation. In group A, cIMT significantly decreased after treatment, whereas no significant changes were observed in group B. In conclusion, our results demonstrate a beneficial effect of the treatment of hyperhomocysteinemia by vitamin supplementation on an early sign of atherosclerosis in a group of renal transplant recipients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vitaminas
/
Artérias Carótidas
/
Transplante de Rim
/
Hiper-Homocisteinemia
/
Homocisteína
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article