[The epidemiology of Helicobacter pylori resistance to antibiotics in Beijing].
Zhonghua Yi Xue Za Zhi
; 85(39): 2754-7, 2005 Oct 19.
Article
em Zh
| MEDLINE
| ID: mdl-16324315
ABSTRACT
OBJECTIVE:
To investigate the prevalence of Helicobacter pylori (H. pylori) resistance to metronidazole, clarithromycin and amoxicillin in Beijing.METHODS:
H. pylori strains were cultured from the gastric biopsy samples obtained from 159 patients with upper abdominal symptoms by gastroendoscopy. Minimal inhibitory concentrations of antibiotics were determined by E-test method.RESULTS:
The resistance rates of H. pylori to metronidazole and clarithromycin in Beijing were 36.0% (18/50) and 10.0% (5/50) in 1999-2000, 43.1% (47/109) and 18.3% (20/109) in 2001-2002, respectively. H. pylori resistance to both metronidazole and clarithromycin were 10.0% (5/50) in 1999-2000 and 14.7% (16/109) in 2001-2002. Only one strain was found resistant to amoxicillin in 49 patients.CONCLUSION:
The resistance rates of H. pylori to metronidazole and clarithromycin were increased in Beijing in recent years. The strains resistant to amoxicillin were rare.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Helicobacter pylori
/
Infecções por Helicobacter
/
Antibacterianos
Tipo de estudo:
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
Zh
Ano de publicação:
2005
Tipo de documento:
Article