Accelerated postnatal head growth follows preterm birth.
Arch Dis Child Fetal Neonatal Ed
; 91(3): F184-7, 2006 May.
Article
em En
| MEDLINE
| ID: mdl-16410256
ABSTRACT
BACKGROUND:
Poor growth after preterm birth, particularly poor head growth, is associated with impaired neurodevelopmental outcome.OBJECTIVE:
To evaluate weight gain and head growth between birth and term in a contemporary cohort of preterm infants, taking into account breast milk intake and illness severity.METHODS:
Subjects were inborn infantsRESULTS:
Infants showed poor postnatal weight gain but accelerated head growth. There was a highly significant fall in mean (SD) weight SDS between birth and discharge (-0.31 (0.96) and -1.32 (1.02) respectively, p<0.001) and a highly significant increase in HC SDS (-0.52 (0.95) and -0.03 (1.25) respectively, p = 0.003). %L1IC had a highly significant negative impact on weight SDSG (p = 0.006), and %BM had a significant positive impact on HC SDSG (p = 0.043).CONCLUSIONS:
Accelerated postnatal head growth suggests catch up after antenatal restraint. This raises the possibility that poor neurocognitive outcomes after extremely preterm birth may in part be consequent on poor intrauterine brain growth. As postnatal head growth may be facilitated by breast milk, there is an urgent need to evaluate the optimal use of breast milk in preterm neonates. Illness severity is a significant determinant of poor postnatal weight gain.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recém-Nascido Prematuro
/
Aumento de Peso
/
Cabeça
Limite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article