Fatal isoflurane hepatotoxicity without re-exposure.
Indian J Gastroenterol
; 25(1): 41-2, 2006.
Article
em En
| MEDLINE
| ID: mdl-16567898
ABSTRACT
Isoflurane is less hepatotoxic than its predecessors, halothane and enflurane. We present a 68-year-old man who developed fulminant and fatal hepatic necrosis two days after open cholecystectomy done under isoflurane anesthesia. Laboratory findings included grossly elevated transaminases and bilirubin and prolonged prothrombin time. Serological studies were negative for viral hepatitis. Postmortem examination demonstrated centrilobular necrosis of liver.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Colecistite
/
Anestésicos Inalatórios
/
Doença Hepática Induzida por Substâncias e Drogas
/
Isoflurano
/
Anestesia Geral
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article