Somatotrophic reorganization in the brain after extremity replantation, revascularization and amputations: investigated by SPECT analysis.
Ulus Travma Acil Cerrahi Derg
; 12(2): 121-8, 2006 Apr.
Article
em En
| MEDLINE
| ID: mdl-16676251
ABSTRACT
BACKGROUND:
We wanted to investigate the somatotropic reorganization occurring in the motor and somatosensory cortex by using 99mTc-HMPAO SPECT analyses, after the extremity revascularization, replantation or amputation.METHODS:
Twelve patients (11 men, 1 female; mean age 38.9+/-14.7 years) and controls (5 men, mean age 32.2+/-7.9 years) were enrolled in this study. After reconstruction, lower, middle and upper orbitomeatal slices with precentral and postcentral slices were obtained. All images were visually and semi-quantitatively evaluated. Mann-Whitney U-test was used for statistical analysis.RESULTS:
In the revascularization and replantation patients, postcentral and precentral hypoperfusions were seen at dominant hemisphere. In the amputated patients, postcentral (in 3 of 4 cases) and precentral hypoperfusions were seen at non-dominant hemisphere and postcentral hypoperfusion (in 1 of 4 cases) was seen at dominant hemisphere. In our patients, most significant difference in regional cerebral blood flow was found in posterior parietal cortex (somatic associated area).CONCLUSION:
Changes that take place in precentral and postcentral cortical areas subsequent to the extremity replantation-revascularization of the organ is a good indicator of somatotrophic reorganization.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Membro Fantasma
/
Córtex Cerebral
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article