Wilson's disease with myoclonus and white matter lesions.
Parkinsonism Relat Disord
; 13(3): 185-8, 2007 Apr.
Article
em En
| MEDLINE
| ID: mdl-16740400
ABSTRACT
White matter lesions (WML) and epilepsy have been occasionally seen in Wilson's disease. No cases of generalized myoclonus have been reported so far. We present a patient with psychiatric symptoms starting at age 16, followed by tremor, generalized dystonia and severe generalized myoclonus. In addition to classical findings, the MRI showed also extensive WML in temporal, parietal and frontal regions, preserving interhemispheric fibers. Necropsy revealed marked alterations of white matter, cortex and basal ganglia. We subsequently review the literature concerning WML and myoclonus in Wilson's disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Cerebral
/
Degeneração Hepatolenticular
/
Mioclonia
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article