[Malignant hereditary paraganglioma: problems raised by non-functional forms management]. / Paragangliomes malins héréditaires: problèmes liés à la prise en charge des formes non sécrétantes.
Ann Chir
; 131(10): 626-30, 2006 Dec.
Article
em Fr
| MEDLINE
| ID: mdl-16815237
ABSTRACT
Non-functional paraganglioma have not clinical or biological characteristics, so that the diagnostic is most of the time delayed and made on the occasion of advanced abdominal tumor or symptomatic metastasis management. Hereditary forms, notably those with SDHB mutation, seem to have a poor prognosis. On the other hand, and on the oposite to sporadic forms, they are the only ones to benefit from genetic testing which make possible, if positive, an earlier diagnostic, before apparition of symptoms, recurrence or metastasis. We report a case of non-functional malignant hereditary paraganglioma diagnosed belatedly and we will consider management problems raised by non-functional forms.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Paraganglioma
/
Neoplasias Abdominais
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
Fr
Ano de publicação:
2006
Tipo de documento:
Article