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Cutaneous mastocytosis: demographic aspects and clinical features of 55 patients.
Akoglu, G; Erkin, G; Cakir, B; Boztepe, G; Sahin, S; Karaduman, A; Atakan, N; Akan, T; Kolemen, F.
Afiliação
  • Akoglu G; Department of Dermatology, Haceteppe University Faculty of Medicine, Ankara, Turkey.
J Eur Acad Dermatol Venereol ; 20(8): 969-73, 2006 Sep.
Article em En | MEDLINE | ID: mdl-16922947
BACKGROUND: Mastocytosis is a rare, heterogeneous group of disorder with abnormal increase of mast cells in one or more organ systems. OBJECTIVE: To evaluate the demographic and clinical features of cutaneous mastocytosis (CM). METHODS: Records of 55 patients with cutaneous mastocytosis were retrospectively analysed. RESULTS: Of the 22 females and 33 males, 80% had urticaria pigmentosa/maculopapular CM and 20% had mastocytoma. Of all cases, 81.8% had first lesions in childhood. The most common presentation was involvement of trunk together with extremities. Thirteen (23.6%) patients had history of bulla; Darier's sign was positive in 34 of 38 patients. Itching was the most common complaint, provocated by hot weather/bath. CONCLUSION: Clinical presentations of urticaria pigmentosa/maculopapular CM and mastocytoma are similar regarding gender, age of onset, age of diagnosis, and presence of Darier's sign and history of bulla. In contrast to mastocytoma, urticaria pigmentosa/maculopapular CM lesions were frequently located on trunk together with extremities.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mastocitose Cutânea Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged / Newborn Idioma: En Ano de publicação: 2006 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mastocitose Cutânea Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged / Newborn Idioma: En Ano de publicação: 2006 Tipo de documento: Article