Perylene-3,4:9,10-tetracarboxylic acid bisimide dye as an artificial DNA base surrogate.
Org Lett
; 8(19): 4191-4, 2006 Sep 14.
Article
em En
| MEDLINE
| ID: mdl-16956184
ABSTRACT
A phosphoramidite of the perylene bisimide dye was synthesized as a DNA building block that allows incorporation of this chromophore as an artificial nucleoside surrogate either at the 5'-terminus or at internal positions of duplex DNA. The internally incorporated perylene bisimide chromophore shows strong interactions with the DNA base stack; the 5'-terminally attached perylene bisimide is able to induce dimerization of two whole DNA duplexes.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Perileno
/
DNA
/
Corantes
/
Imidas
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article