Kainate receptor-interacting proteins and membrane trafficking.
Biochem Soc Trans
; 34(Pt 5): 927-30, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17052229
ABSTRACT
Kainate receptors are composed of several subunits and splice variants, but the relevance of this diversity is still not well understood. The subunits and splice variants show great divergence in their C-terminal cytoplasmic tail region, which has been identified as a region of interaction with a number of protein partners. Differential trafficking of kainate receptors to neuronal compartments is likely to rely on interactions with distinct subsets of protein partners. This review summarizes our knowledge of the regulation of trafficking of kainate receptors and focuses on the identification and characterization of functions of interacting partners.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Membrana Celular
/
Receptores de Ácido Caínico
/
Proteínas de Membrana
Limite:
Aged
/
Humans
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article